Thyroid Hormone Drives Curiosity and Exploratory Conduct, Research Finds

The right way to Use Progesterone

Earlier than you think about using progesterone, it is very important perceive that it isn’t a magic bullet, and that you simply get essentially the most profit by implementing a Bioenergetic weight loss plan method that lets you successfully burn glucose as your major gas with out backing up electrons in your mitochondria that reduces your vitality manufacturing. My new e-book, “Your Information to Mobile Well being: Unlocking the Science of Longevity and Pleasure” comes out very quickly and covers this course of in nice element.

After you have dialed in your weight loss plan, an efficient technique that may assist counteract estrogen extra is to take transmucosal progesterone (i.e., utilized to your gums, not oral or transdermal), which is a pure estrogen antagonist. Progesterone is one among solely 4 hormones I consider many adults can profit from. (The opposite three are thyroid hormone T3, DHEA and pregnenolone.)

I don’t advocate transdermal progesterone, as your pores and skin expresses excessive ranges of 5-alpha reductase enzyme, which causes a good portion of the progesterone you are taking to be irreversibly transformed primarily into allopregnanolone and can’t be transformed again into progesterone.

Best Option to Administer Progesterone

Please word that when progesterone is used transmucosally in your gums as I counsel, the FDA believes that by some means converts it right into a drug and prohibits any firm from advising that on its label. For this reason corporations like Well being Natura promotes their progesterone merchandise as “topical.”

Nonetheless, please perceive that it’s completely authorized for any doctor to advocate an off-label indication for a drug to their affected person. On this case, progesterone is a pure hormone and never a drug and could be very protected even in excessive doses. That is not like artificial progesterone referred to as progestins which can be utilized by drug corporations, however ceaselessly, and incorrectly, referred.

Dr. Ray Peat has performed the seminal work in progesterone and doubtless was the world’s biggest knowledgeable on progesterone. He wrote his Ph.D. on estrogen in 1982 and spent most of his skilled profession documenting the necessity to counteract the hazards of extra estrogen with low LA diets and transmucosal progesterone supplementation.

He decided that almost all solvents don’t dissolve progesterone nicely and found that vitamin E is the very best solvent to optimally present progesterone in your tissue. Vitamin E additionally protects you towards harm from LA. You simply should be very cautious about which vitamin E you utilize as most supplemental vitamin E available on the market is worse than nugatory and can trigger you hurt not profit.

It’s crucial to keep away from utilizing any artificial vitamin E (alpha tocopherol acetate — the acetate signifies that it is artificial). Pure vitamin E might be labeled “d alpha tocopherol.” That is the pure D isomer, which is what your physique can use.

There are additionally different vitamin E isomers, and also you need the whole spectrum of tocopherols and tocotrienols, particularly the beta, gamma, and delta sorts, within the efficient D isomer. For instance of a great vitamin E, you may take a look at the label on our vitamin E in our retailer. You should use any model that has an analogous label.

You should buy pharmaceutical grade bioidentical progesterone as Progesterone Powder, Bioidentical Micronized Powder, 10 grams for about $40 on many on-line shops like Amazon. That’s almost a yr’s provide, relying on the dose you select.

Nonetheless, you will want to buy some small chrome steel measuring spoons as you will want a 1/64 tsp, which is 25 mg and a 1/32 tsp, which is 50 mg. A traditional dose is usually 25-50 mg and is taken half-hour earlier than mattress, because it has an anti-cortisol perform and can enhance GABA ranges for a great night time’s sleep.

Sadly, this vendor ceaselessly runs out of product, and if that’s the case, then you should utilize Merely Progesterone by Well being Natura. It’s premixed with vitamin E and MCT oil. Once more, whereas Well being Natura states that its product is for “topical use solely,” I like to recommend making use of it transmucosally, by rubbing it in your gums.

If you’re a menstruating lady, it is best to take the progesterone through the luteal section or the final half of your cycle, which might be decided by beginning 10 days after the primary day of your interval and stopping the progesterone when your interval begins.

If you’re a male or non-menstruating lady, you may take the progesterone day-after-day for 4 to 6 months after which cycle off for one week. The perfect time of day to take progesterone is half-hour earlier than mattress because it has an anti-cortisol perform and can enhance GABA ranges for a great night time’s sleep.

That is what I’ve been personally doing for over a yr with excellent outcomes. I’m a doctor so would not have any issues doing this. In the event you aren’t a doctor, it is best to seek the advice of one earlier than utilizing this remedy, as transmucosal progesterone remedy requires a physician’s prescription.