In immediately’s health-conscious world, dietary dietary supplements have change into a well-liked software for filling dietary gaps, bettering total well-being, and even managing particular well being circumstances. Nonetheless, not all dietary supplements are created equal. Some may be contaminated, work together with drugs, and even hurt liver well being. Choosing the proper complement requires cautious consideration and consciousness of potential dangers, and it additionally means being conscious of shady advertising and marketing ways!
This publish will discover the hazards of complement use, current analysis highlighting the dangers of supplement-induced liver failure, and sensible steps you may take to guard your well being.
‘Dietary supplements’ is an umbrella time period for supplemental types of particular person vitamins like calcium and iron. However the extra problematic of the bunch are ‘pure’ dietary dietary supplements which are marketed with shady claims, proprietary formulation, and little to no testing. These are the sorts of dietary supplements that I’m principally referring to on this publish.
The Hidden Risks of Dietary supplements: Liver Failure, Current Analysis, and The way to Keep Protected
Dietary dietary supplements are a multi-billion-dollar business, marketed as a simple manner to enhance well being, improve vitality, and fill in dietary gaps. Nonetheless, behind the shiny labels and well being claims, a rising physique of analysis reveals that some dietary supplements can pose critical well being dangers—together with liver failure.

Lately, circumstances of supplement-induced liver damage (SILI) have been on the rise, with sure natural and dietary dietary supplements linked to extreme liver harm, hospitalization, and even demise. Regardless of being broadly accessible over-the-counter and sometimes perceived as “pure” and secure, many dietary supplements are poorly regulated and might include dangerous elements.
Complement Advertising and marketing is a Dumpster Hearth
‘But it surely’s pure!’ So are toxic mushrooms, however no one desires to eat these. The complement business – particularly the vitamin complement business – is constructed on convincing individuals to purchase dietary supplements that we truly don’t want.
Implying that dietary supplements are extra ‘pure’ than drugs works on the Enchantment to Nature fallacy, which complement makers use to make their product seem safer than prescription drugs. As a dietitian, I’m seeing this rather a lot with GLP-1 dietary supplements, that are principally simply rubbish. Nothing about them is efficient or safer than precise drugs, that are regulated and prescribed beneath managed circumstances (ideally…everyone knows one thing who’s getting them from doubtful sources).
I used to be unreasonably comfortable to see that Kourtney Kardashian’s Lemme GLP-1 complement is at present the topic of a category motion lawsuit for claiming to work like GLP-1 agonist treatment. It doesn’t. However as I wrote in one among my current posts, there are a lot of individuals who need GLP-1 treatment however can’t afford it. This leaves a niche that’s being grossly exploited by the complement business.


That’s how shady complement makers earn their cash, and it typically works…to the tune of $177 billion {dollars} in 2023, and projected to develop exponentially for the forseeable future. Whether or not it’s weight reduction, menopause, blood sugar (see my Glucose Goddess Anti Spike evaluate right here), immunity-boosting, or no matter else, the complement business has a capsule for that.
It goes with out saying that if a complement is claiming to treatment anxiousness or melancholy or every other psychological well being analysis, it’s an enormous purple flag. Claims like these are unethical and doubtlessly harmful, as they will persuade individuals to desert efficient and mandatory treatment.
Getting clever to complement advertising and marketing scams takes a number of small checks.
Diet Complement Crimson Flags:
No analysis, or basing claims on animal or cell analysis. Even in the event you aren’t well-versed in studying analysis, all the time check out the complement’s web site to see if it provides analysis to again up its claims. Is the analysis accomplished on people? Animals? How outdated are the research? Is the analysis accomplished on the product itself, or solely on sure elements that the product accommodates?
I wrote a publish about the fundamentals of deciphering vitamin analysis right here, however the TL;DR is that you really want current research (as in, final 5 years), accomplished in people, revealed in peer-reviewed journals, on the product itself. 99% of the time, you received’t discover all of these issues. That could be a purple flag.
Something offered by multi-level advertising and marketing. Not solely do MLM corporations prey on susceptible individuals (primarily ladies), they have an inclination to take advantage of egregious claims about their merchandise. MLM salespeople will not be skilled to offer vitamin recommendation or perceive your well being historical past. Belief me – if one thing groundbreaking exists, it is going to be regulated by the FDA and offered in drugstores, not by some MLM coach.


Implying that their system was found by ‘Harvard (or X Ivy League) scientists’ or that Large Pharma/precise scientists haven’t but found this groundbreaking secret. I see this rather a lot from corporations like VShred (learn my VShred evaluate right here) and Lifevantage (learn my Lifevantage Protandim and GLP-1 evaluate right here), amongst many others. There isn’t any large secret. No one is hiding something (moreover these corporations attempting to cover their grift, though they aren’t fooling me!). Title dropping an Ivy League faculty by no means means something, both. It’s all bluster created to offer them false legitimacy.
Claiming {that a} complement can treatment the incurable, akin to autism, ADHD. Don’t even go there.
Large claims and use of statistics that appear too good to be true. 95% of individuals love this complement? How did the corporate even decide that? Trace: they didn’t.


Using earlier than and after photographs and testimonials to ‘show’ efficacy of a product. These are simply faked, they usually present up when an organization has nothing higher to supply when it comes to proof of their product working.
The declare of being safer, extra pure, or equally efficient as precise drugs. We talked about this above.


Obscure claims utilizing phrases or phrases like ‘helps metabolism’ or ‘helps with X’. That is how corporations could make the claims they make, with out triggering the FDA’s consideration. It’s a loophole that many individuals don’t find out about, however now you do!
Using influencers to promote the product. This one could be controversial, however I really feel like widespread influencers utilizing affiliate codes to flood peoples’ social feeds with advertisements for a product is a distraction and made to persuade potential prospects that in the event that they use the product, they’ll be younger/enticing/wholesome/widespread just like the individuals promoting it.
The Risks of Diet Dietary supplements
Whereas all vitamin dietary supplements are marketed as helpful, they will generally do extra hurt than good. A few of the key dangers embody:
Lack of Regulation
The U.S. Meals and Drug Administration (FDA) regulates dietary supplements beneath the Dietary Complement Well being and Training Act (DSHEA) of 1994, which permits producers to promote merchandise with out proving their security or efficacy. Not like prescribed drugs, dietary dietary supplements will not be required to endure rigorous testing earlier than hitting the market.
Which means:
Dietary supplements could include unlisted or dangerous elements.
Dosages could also be inconsistent or larger than really helpful.
Contaminants akin to heavy metals, pesticides, or prescribed drugs could also be current.
The FDA usually doesn’t become involved until there has truly been hurt accomplished to an individual by the complement.


Liver Toxicity and Organ Harm
The liver performs an important position in processing dietary supplements, breaking down compounds, and detoxifying dangerous substances. Nonetheless, sure dietary supplements include elements that may overwhelm or harm liver cells, resulting in:
Hepatotoxicity (liver toxicity): The liver struggles to course of poisonous compounds, resulting in irritation and cell harm.
Acute liver failure: Extreme circumstances the place the liver loses its skill to operate, generally requiring a transplant or leading to demise.
Persistent liver illness: Lengthy-term harm from repeated publicity to dangerous dietary supplements.
Harmful Interactions with Drugs
Many individuals take dietary supplements alongside prescription drugs with out realizing that sure mixtures may be poisonous.
For instance, St. John’s Wort can scale back the effectiveness of antidepressants and contraception tablets. Kava and inexperienced tea extracts have been linked to extreme liver harm, particularly when taken with different drugs metabolized by the liver. Vitamin A and iron in extreme doses could cause liver irritation and harm.
Current Analysis on Complement-Induced Liver Failure
Over the previous decade, scientific research and medical reviews have highlighted a regarding rise in supplement-related liver damage.


The DILIN Research (2014 – Current)
The Drug-Induced Liver Harm Community (DILIN), a U.S.-based analysis initiative, has been monitoring circumstances of drug- and supplement-related liver damage.
Their findings present that:
Natural and dietary dietary supplements account for 20% of liver damage circumstances within the U.S.
The speed of supplement-induced liver harm has elevated from 7% in 2004 to twenty% lately.
Weight-loss and bodybuilding dietary supplements are probably the most generally implicated.
Inexperienced Tea Extracts and Hepatotoxicity
Inexperienced tea extract is a well-liked complement discovered in lots of weight-loss merchandise, however analysis has linked it to extreme liver toxicity.
A 2018 examine within the journal Hepatology discovered that catechins, the energetic compounds in inexperienced tea, could cause liver harm in excessive doses. Some circumstances resulted in acute liver failure requiring transplants. A 2022 examine discovered garcinia cambogia, with or with out inexperienced tea (I’ve seen numerous dietary supplements that include each of those elements) could cause reasonable to extreme liver damage.


Bodybuilding Dietary supplements and Undisclosed Steroids
Bodybuilding dietary supplements are among the many most harmful, with many containing undeclared anabolic steroids that may trigger liver toxicity.
A 2017 examine in The Journal of Gastroenterology and Hepatology discovered that:
Practically 50% of liver damage circumstances in younger males have been linked to bodybuilding dietary supplements.
Many of those dietary supplements contained unlawful or undisclosed steroid compounds.
Heavy metals like arsenic, micro organism and fungi, banned stimulants like ephedrine, and undeclared medication like sibutramine (discovered to have cardiac dangers) are only some examples of what has not too long ago been present in natural vitamin dietary supplements.
Whereas not all dietary supplements are dangerous, it’s important to method them with warning. Right here’s the way to shield your self:
Do Your Analysis Earlier than Taking Any Complement
Search for scientific research that assist the security and effectiveness of a complement.
Be skeptical of merchandise that promise speedy weight reduction, excessive muscle acquire, or “detox” advantages. If one thing is promising to do what no different complement or treatment has accomplished earlier than (ie fats burners), stroll or scroll proper on by. Whereas a complement may not be harmful, I additionally contemplate the monetary impacts of taking something you don’t actually need.


Select Third-Get together Examined Dietary supplements
For the reason that FDA doesn’t regulate dietary supplements strictly, search for third-party testing from organizations akin to:
U.S. Pharmacopeia (USP)
NSF Worldwide
ConsumerLab
These certifications be sure that dietary supplements include what they declare and shouldn’t have dangerous contaminants.
Keep away from Excessive-Threat Dietary supplements
A few of the most harmful dietary supplements embody:
Inexperienced tea extract (excessive doses)
Kava
Kratom
Bodybuilding dietary supplements with steroids
Weight-loss dietary supplements with “fats burners” or stimulants
Discuss to Your Physician Earlier than Utilizing Dietary supplements
If you’re on drugs, ask your physician about doable complement interactions.
When you have liver illness, diabetes, or coronary heart circumstances, be further cautious with dietary supplements.
In Brief:
Dietary dietary supplements may be useful in some circumstances, however additionally they pose important dangers—particularly to liver well being. With analysis linking sure dietary supplements to liver failure, it’s essential to learn and selective about what you are taking.
By selecting third-party examined merchandise, avoiding high-risk dietary supplements, and prioritizing entire meals, you may shield your liver and total well being. At all times seek the advice of with a healthcare skilled earlier than including any new complement to your routine.
Your well being is price greater than a fast repair—keep knowledgeable, and keep secure!